President Donald Trump signaled a tough stance on drug trafficking from Latin America, saying he would consider targeting drug routes, production facilities, and shipments—even in Mexico—if it could save American lives. Speaking to reporters, Trump claimed U.S. forces have drastically reduced drug inflows through waterways, preventing tens of thousands of deaths, and expressed willingness to extend such operations to land-based smuggling corridors. He specifically mentioned fentanyl and cocaine shipments from Colombia and emphasized that U.S. intelligence tracks the locations of drug lords and their networks. The remarks come amid the ongoing U.S. “war on drugs,” which has historically included cross-border cooperation, interdiction efforts, and occasional military-style operations in Latin America to “combat cartels responsible for tens of thousands of overdose deaths annually.”